A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases

Analysis of 40 common human brain diseases identifies 5 major transcriptional patterns, representing tumor-related, neurodegenerative, psychiatric and substance abuse, and 2 mixed groups of diseases affecting basal ganglia and hypothalamus.

#Neuroscience #Brain #Neurology #NeurologicalDiseases #Psychiatry #PsychiatricDiseases #MentalDiseases #NeurodegenerativeDiseases #Neurodegeneration #NeurogeneticDiseases #Neurogenetics #Transcriptome #Transcriptomics #Genomics #MolecularBiology #Biomedicine

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002058